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1

Notch 1 interacts with the amyloid precursor protein in a Numb-independent manner

Angeliki Fassa, Pankaj Mehta, Spiros Efthimiopoulos

Journal:

Journal of Neuroscience Research

Année:

2005

Langue:

english

Fichier:

PDF, 742 KB

english, 2005

2

Intracellular Cyclic AMP Inhibits Constitutive and Phorbol Ester-Stimulated Secretory Cleavage of Amyloid Precursor Protein

Spiros Efthimiopoulos, Suzy Punj, Vangelis Manolopoulos, Menelas Pangalos, Gian P. Wang, Lawrence M. Refolo, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 449 KB

english, 1996

3

Enrichment of Presenilin 1 Peptides in Neuronal Large Dense-Core and Somatodendritic Clathrin-Coated Vesicles

Spiros Efthimiopoulos, Erik Floor, Anastasios Georgakopoulos, Junichi Shioi, Wen Cui, Sukkid Yasothornsrikul, Vivian Y. H. Hook, Thomas Wisniewski, Luc Buee, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 1000 KB

english, 1998

4

Distinct Secretases, a Cysteine Protease and a Serine Protease, Generate the C Termini of Amyloid β-Proteins Aβ1-40 and Aβ1-42, Respectively

Maria E. Figueiredo-Pereira, Spiros Efthimiopoulos, Nikolaos Tezapsidis, Angeliki Buku, Jorge Ghiso, Pankaj Mehta, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 196 KB

english, 1999

5

Presenilin-1: A Component of Synaptic and Endothelial Adherens Junctions

ANASTASIOS GEORGAKOPOULOS, PHILIPPE MARAMBAUD, VICTOR L. FRIEDRICH JR., JUNICHI SHIOI, SPIROS EFTHIMIOPOULOS, NIKOLAOS K. ROBAKIS

Journal:

Annals of the New York Academy of Sciences

Année:

2000

Langue:

english

Fichier:

PDF, 770 KB

english, 2000

6

BRI2 as a central protein involved in neurodegeneration

Maria Tsachaki, Jorge Ghiso, Spiros Efthimiopoulos

Journal:

Biotechnology Journal

Année:

2008

Langue:

english

Fichier:

PDF, 241 KB

english, 2008

7

Cell-Line Specific Protection by Berry Polyphenols Against Hydrogen Peroxide Challenge and Lack of Effect on Metabolism of Amyloid Precursor Protein

Magdalini A. Papandreou, Maria Tsachaki, Spiros Efthimiopoulos, Dorothy Klimis-Zacas, Marigoula Margarity, Fotini N. Lamari

Journal:

Phytotherapy Research

Année:

2012

Langue:

english

Fichier:

PDF, 298 KB

english, 2012

8

Abeta(1–40)-induced secretion of matrix metalloproteinase-9 results in sAPPα release by association with cell surface APP

Argiris A. Talamagas, Spiros Efthimiopoulos, Effie C. Tsilibary, Maria E. Figueiredo-Pereira, Athina K. Tzinia

Journal:

Neurobiology of Disease

Année:

2007

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2007

9

Homer2 and Homer3 interact with amyloid precursor protein and inhibit Aβ production

Loukia Parisiadou, Ioanna Bethani, Vasiliki Michaki, Kaliopi Krousti, Georgia Rapti, Spiros Efthimiopoulos

Journal:

Neurobiology of Disease

Année:

2008

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2008

10

Memory enhancing effects of saffron in aged mice are correlated with antioxidant protection

Magdalini A. Papandreou, Maria Tsachaki, Spiros Efthimiopoulos, Paul Cordopatis, Fotini N. Lamari, Marigoula Margarity

Journal:

Behavioural Brain Research

Année:

2011

Langue:

english

Fichier:

PDF, 772 KB

english, 2011

11

Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11α

Loukia Parisiadou, Spiros Efthimiopoulos

Journal:

Neurobiology of Aging

Année:

2007

Langue:

english

Fichier:

PDF, 906 KB

english, 2007

12

BRI2 homodimerizes with the involvement of intermolecular disulfide bonds

Maria Tsachaki, Jorge Ghiso, Agueda Rostagno, Spiros Efthimiopoulos

Journal:

Neurobiology of Aging

Année:

2010

Langue:

english

Fichier:

PDF, 701 KB

english, 2010

13

Molecular organization of presenilin 1 in the E-cadherin/catenins cell adhesion system

Philippe Marambaud, Lia Baki, Anastasios Georgakopoulos, Junichi Shioi, Spiros Efthimiopoulos, Masayuki Ozawa, Nikolaos K. Robakis

Journal:

Neurobiology of Aging

Année:

2000

Langue:

english

Fichier:

PDF, 190 KB

english, 2000

14

Localization of presenilin at synaptic sites

Tassos Georgakopoulos, Junichi Shioi, Ronald Gordon, Gay R. Holstein, Giorgio Martinelli, Spiros Efthimiopoulos, Victor L. Friedrich, Nikolaos K. Robakis

Journal:

Neurobiology of Aging

Année:

2000

Langue:

english

Fichier:

PDF, 186 KB

english, 2000

15

PS1 is a regulatory component of the cadherin/catenin adherens junction system

Lia Baki, Philippe Marambaud, Spiros Efthimiopoulos, Paul Wen, Tassos Georgakopoulos, Nikolaos K. Robakis

Journal:

Neurobiology of Aging

Année:

2000

Langue:

english

Fichier:

PDF, 113 KB

english, 2000

16

Inhibition of neurite outgrowth by familial Alzheimer's disease-linked presenilin-1 mutations

Wieslaw K. Dowjat, Thomas Wisniewski, Spiros Efthimiopoulos, Henryk M. Wisniewski

Journal:

Neuroscience Letters

Année:

1999

Langue:

english

Fichier:

PDF, 316 KB

english, 1999

17

Presenilin-1 Forms Complexes with the Cadherin/Catenin Cell–Cell Adhesion System and Is Recruited to Intercellular and Synaptic Contacts

Anastasios Georgakopoulos, Philippe Marambaud, Spiros Efthimiopoulos, Junichi Shioi, Wen Cui, Heng-Chun Li, Michael Schütte, Ronald Gordon, Gay R Holstein, Giorgio Martinelli, Pankaj Mehta, Victor L F

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 389 KB

english, 1999

18

O2-03-06: BRI2 modulates amyloid precursor protein processing and inhibits aβ generation

Maria Tsachaki, Angeliki Fotinopoulou, Maria Vlavaki, Alexandros Poulopoulos, Agueda Rostagno, Blas Frangione, Jorge Ghiso, Spiros Efthimiopoulos

Journal:

Alzheimer's & Dementia

Année:

2006

Langue:

english

Fichier:

PDF, 58 KB

english, 2006

19

Characterization of Appican, the Chondroitin Sulfate Proteoglycan Form of the Alzheimer Amyloid Precursor Protein

Menelas N. Pangalos, Junichi Shioi, Spiros Efthimiopoulos, Anfan Wu, Nikolaos K. Robakis

Journal:

Neurodegeneration

Année:

1996

Langue:

english

Fichier:

PDF, 75 KB

english, 1996

20

Cellular Processing and Proteoglycan Nature of Amyloid Precursor Proteins

NIKOLAOS K. ROBAKIS, DIDO VASSILACOPOULOU, SPIROS EFTHIMIOPOULOS, KUMAR SAMBAMURTI, LAWRENCE M. REFOLO, JUNICHI SHIOI

Journal:

Annals of the New York Academy of Sciences

Année:

1993

Langue:

english

Fichier:

PDF, 420 KB

english, 1993

21

Calcium regulates the interaction of amyloid precursor protein with Homer3 protein

Kyratzi, Elli, Efthimiopoulos, Spiros

Journal:

Neurobiology of Aging

Année:

2014

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2014

22

Chondroitin sulfate proteoglycan form of cellular and cell-surface Alzheimer amyloid precursor

Shioi, Junichi, Refolo, Lawrence M., Efthimiopoulos, Spiros, Robakis, Nikolaos K.

Journal:

Neuroscience Letters

Année:

1993

Langue:

english

Fichier:

PDF, 453 KB

english, 1993

23

Cholinergic Agonists Stimulate Secretion of Soluble Full-Length Amyloid Precursor Protein in Neuroendocrine Cells

Spiros Efthimiopoulos, Dido Vassilacopoulou, James A. Ripellino, Nikolaos Tezapsidis and Nikolaos K. Robakis

Journal:

Proceedings of the National Academy of Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1996

24

Release of Nontransmembrane Full-Length Alzheimer's Amyloid Precursor Protein from the Lumenar Surface of Chromaffin Granule Membranes †

Tezapsidis, Nikolaos, Li, Heng-Chun, Ripellino, James A., Efthimiopoulos, Spiros, Vassilacopoulou, Dido, Sambamurti, Kumar, Toneff, Thomas, Yasothornsrikul, Sukkid, Hook, Vivian Y. H., Robakis, Nikola

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 129 KB

english, 1998

25

Synthesis and evaluation of gallocyanine dyes as potential agents for the treatment of Alzheimer's disease and related neurodegenerative tauopathies

Mpousis, Spyros, Thysiadis, Savvas, Avramidis, Nicolaos, Katsamakas, Sotirios, Efthimiopoulos, Spiros, Sarli, Vasiliki

Journal:

European Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2016

26

Presenilin 1 and Cadherins: Stabilization of Cell-Cell Adhesion and Proteolysis-Dependent Regulation of Transcription

Parisiadou, Loukia, Fassa, Angeliki, Fotinopoulou, Angeliki, Bethani, Ioanna, Efthimiopoulos, Spiros

Journal:

Neurodegenerative Diseases

Année:

2004

Langue:

english

Fichier:

PDF, 161 KB

english, 2004

27

Novel Processing of Notch 1 within Its Intracellular Domain by a Cysteine Protease

Fassa, Angeliki, Parisiadou, Loukia, Robakis, Nikolaos K., Efthimiopoulos, Spiros

Journal:

Neurodegenerative Diseases

Année:

2007

Langue:

english

Fichier:

PDF, 197 KB

english, 2007

28

A novel Polish presenilin-1 mutation (P117L) is associated with familial Alzheimerʼs disease and leads to death as early as the age of 28 years

Wisniewski, Thomas, Dowjat, Wieslaw K., Buxbaum, Joseph D., Khorkova, Olga, Efthimiopoulos, Spiros, Kulczycki, Jerzy, Lojkowska, Wanda, Wegiel, Jerzy, Wisniewski, H M., Frangione, B

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 545 KB

english, 1998

29

Oxygen and Glucose Deprivation Alter Synaptic Distribution of Tau Protein: The Role of Phosphorylation

Mavroeidi, Panagiota, Mavrofrydi, Olga, Pappa, Elpiniki, Panopoulou, Myrto, Papazafiri, Panagiota, Haralambous, Sylva, Efthimiopoulos, Spiros

Journal:

Journal of Alzheimer's Disease

Année:

2017

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2017

30

Design and Synthesis of Gallocyanine Inhibitors of DKK1/LRP6 Interactions for Treatment of Alzheimer ’s Disease

Thysiadis, Savvas, Katsamakas, Sotirios, Mpousis, Spyros, Avramidis, Nicolaos, Efthimiopoulos, Spiros, Sarli, Vasiliki

Journal:

Bioorganic Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2018

31

Amyloid precursor protein regulates depolarization-induced calcium-mediated signaling in brain slices

Efthimiopoulos, Spiros, Chatzistavraki, Maria, Papazafiri, Panagiota

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 61 KB

english, 2019

32

Investigation of genetic base in the treatment of age-related macular degeneration

Gourgouli, Kalliopi, Gourgouli, Ioanna, Tsaousis, Georgios, Spai, Sofia, Niskopoulou, Maria, Efthimiopoulos, Spiros, Lamnissou, Klea

Journal:

International Ophthalmology

Année:

2020

Fichier:

PDF, 556 KB

2020

33

Amyloid-Î² Protein Precursor Regulates Depolarization-Induced Calcium-Mediated Synaptic Signaling in Brain Slices

Chatzistavraki, Maria, Papazafiri, Panagiota, Efthimiopoulos, Spiros

Journal:

Journal of Alzheimer's Disease

Année:

2020

Fichier:

PDF, 637 KB

2020